Professor
Meijo University
04/1991 - 03/1999 Research Associate and Assistant Professor of Nagoya University
04/1999 - 09/2003 Associate Professor of Faculty of Systems Eng., Wakayama University
10/2003 - 03/2009 Professor of Faculty of Systems Eng., Wakayama University
04/2009 - Present Professor of Faculty of Science and Technology, Meijo University
04/2014 - 03/2019 Director of Research Center for Plasma-Bio Science and Technology
Publications, Meijo University
04/2019 - Present Director of Research Center for Plasma-Bio Applications, Meijo University
In this study, we have investigated the bactericidal and plant growth effects of compounds with ring structures. The survival number of alive E. coli or Staphylococcus aureus (S. aureus) decreased in the oxygen-radical exposed solutions including L-tryptophan (L-Trp), which is also a kind of amino acids, and reached the detection limit of colony forming unit assay by 1-min or 5-min exposure, respectively. To identify essential chemical structure to produce the rapid bactericidal effects of oxygen-radical irradiation to L-Trp, E. coli was suspended into PB solutions (pH 6.3) containing benzene, pyrrole or indole. The concentrations of benzene, pyrrole or indole was set at 1 mM. 3 mL of the E. coli suspension in a φ38-mm sterile dish was treated using the oxygen-radical generator for 0 or 5 min. 6-log reduction of E. coli survival number was achieved only in the cases of pyrrole or indole solutions. Therefore, oxygen-radical irradiation to pyrrolic compounds was suggested as a key to produce the rapid bactericidal effect. This work was supported by JSPS KAKENHI Grant Number JP19H05462 and JP24H02254.
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email: plasma@drexel.edu
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